Value of MR Venography for Detection of Internal Jugular Vein Anomalies in Multiple Sclerosis: A Pilot Longitudinal Study.

  • [zivadinov11a] Zivadinov R, Galeotti R, Hojnacki D, Menegatti E, Dwyer MG, Schirda C, Malagoni AM, Marr K, Kennedy C, Bartolomei I, Magnano C, Salvi F, Weinstock-Guttman B, and Zamboni P: Value of MR Venography for Detection of Internal Jugular Vein Anomalies in Multiple Sclerosis: A Pilot Longitudinal Study. AJNR Am J Neuroradiol. 2011 Apr:. PMID 21474626, doi:10.3174/ajnr.A2386. PDF.
    Buffalo Neuroimaging Analysis Center, State University of New York, Buffalo, New York; Jacobs Neurological Institute, State University of New York, Buffalo, New York; and Vascular Diseases Center, University of Ferrara-Bellaria Neurosciences, Ferrara and Bologna, Italy.

Studies of Zivadinov and Zamboni

MR venography seems not to be helpful according to the study of Zivadinov.
  • [zamboni11a] Zamboni P, and Carinci F: Face, brain, and veins: a new perspective for multiple sclerosis onset. J Craniofac Surg. 2011 Jan;22(1):376. PMID 21239945, doi:10.1097/SCS.0b013e3181f81652.
    1Vascular Disease Center, University of Ferrara, Ferrara, Italy 2Maxillofacial Surgery, University of Ferrara, Ferrara, Italy.
  • [zivadinov10b] Zivadinov R, Lopez-Soriano A, Weinstock-Guttman B, Schirda CV, Magnano CR, Dolic K, Kennedy CL, Brooks CL, Reuther JA, Hunt K, Andrews M, Dwyer MG, and Hojnacki DW: Use of MR Venography for Characterization of the Extracranial Venous System in Patients with Multiple Sclerosis and Healthy Control Subjects. Radiology. 2010 Dec:. PMID 21177394, doi:10.1148/radiol.10101387.
    Department of Neurology, School of Medicine and Biomedical Sciences, Buffalo Neuroimaging Analysis Center, State University of New York, 100 High St., Buffalo, NY 14203.

New publications of Zamboni and Simka in December

  • [zamboni10e] Zamboni P, and Galeotti R: The chronic cerebrospinal venous insufficiency syndrome. Phlebology. 2010 Dec;25(6):269-79. PMID 21106999, doi:10.1258/phleb.2010.009083.
    Vascular Disease Centre, Interventional Radiology Unit, University of Ferrara, 44100 Ferrara
  • [ludyga10a] Ludyga T, Kazibudzki M, Simka M, Hartel M, Swierad M, Piegza J, Latacz P, Sedlak L, and Tochowicz M: Endovascular treatment for chronic cerebrospinal venous insufficiency: is the procedure safe? Phlebology. 2010 Dec;25(6):286-95. PMID 21107001, doi:10.1258/phleb.2010.010053.
    EUROMEDIC Specialist Clinics, Department of Vascular & Endovascular Surgery, Katowice, Poland.

New publications and announced studies - updated 2

New publications

  • [ferlini10a] Ferlini A, Bovolenta M, Neri M, Gualandi F, Balboni A, Yuryev A, Salvi F, Gemmati D, Liboni A, and Zamboni P: Custom CGH array profiling of copy number variations (CNVs) on chromosome 6p21.32 (HLA locus) in patients with venous malformations associated with multiple sclerosis. BMC Med Genet. 2010 Apr;11(1):64. Epub 2010 Apr 28. PMID 20426824, doi:10.1186/1471-2350-11-64. Article, PDF.
  • [qiu10a] Qiu J: Venous abnormalities and multiple sclerosis: another breakthrough claim? Lancet Neurol. 2010 May;9(5):464-5. PMID 20398855, doi:10.1016/S1474-4422(10)70098-3.
  • [beal10a] Beal E: Vascular angioplasty for ms? Nat Rev Neurol. 2010 Apr;6(4):184. PMID 20383884. Article$.
  • [rynor10a] Rynor B: Canadian trials to examine "liberation procedure" for multiple sclerosis. CMAJ. 2010 May:. PMID 20439450, doi:10.1503/cmaj.109-3251. PDF. See [trial_rodger10a] [trial_knox10a]

Announced studies

  • [trial_zamboni10a] Zamboni P: Randomised controlled CCSVI treatment trial. Source (medpage interview at 2:15)
    IRB: June 2010
    Start: Summer 2010
  • [trial_dake10a] Dake M: CCSVI Study. Stanford University. Source (Video interview). Needs funding. new
    Stanford University
  • [trial_sinan10a] Sinan T, Al Khashan S, Safar H, Almuzaini AA, Bin naki AM, Al bader M, Bahzad M: CCSVI study Kuwait. Study description, Introduction.
    Mubarak Hospital and other Hospitals of Kuwait
  • [trial_hubbard10a] Hubbard D: The fMRI BOLD Response in MS, Support for the CCSVI Hypothesis. Hubbard Foundation for fMRI Research. Grant Request (PDF)
    Hubbard Foundation for fMRI Research.
  • [trial_tornatore10a] Tornatore C, Neville R: CCSVI treatment study. Georgetown University Hospital. Source
    Georgetown University Hospital, USA

Comparison by Charity Intelligence Canada of the Canadian studies [trial_rodger10a] and [trial_knox10a] which are seeking funding: PDF document.

Note: Kuwait offers angioplasty for CCSVI to all Kuwaitis affected by MS through the public health system. Source: CTV.

Related studies

CTV W5 – The Liberation War – Online

CTV W5 show is available:

Liberation War – Why MS patients aren't waiting for proof

Live CCSVI Webcast at AAN conference 14 Apr 12 pm ET (Toronto) / 18h MESZ (Zürich)

On April 14th, the MS Society and the American Academy of Neurology will hold a live web forum about CCSVI and MS. Anyone can attend.

Update: Online viewer for all who have missed the live webcast updated

This webcast takes place while the American Academy of Neurology (AAN) Annual Meeting, Toronto, 10–17 Apr 2010.

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