Venöse Multiple Sklerose Hypothese | CCSVI

1. PDFs are available for free of the Int Angiol. 2010 Apr;29(2) issue. Check out the previous article.

2. [doepp10a] Doepp F, Paul F, Valdueza JM, Schmierer K, Schreiber SJ: No cerebro-cervical venous congestion in patients with multiple sclerosis. Annals of Neurology. 2010. doi:10.1002/ana.22085. Article$
   Department of Neurology, University Hospital Charité, Humboldt University, Berlin, Germany; Barts and The London Queen Mary School of Medicine & Dentistry, London, UK

Die Ausgabe 2010 April;29(2) des International Angiology Journals ist CCSVI gewidmet und enthält 13 Beiträge zu CCSVI. Ein weiterer Artikel über einen Zusammenhang zwischen Gefässproblemen und Multiple Sklerose.

1. [zamboni10c] Zamboni P: Chronic cerebrospinal venous insufficiency. Int Angiol. 2010 Apr;29(2):91-2. PMID 20351663. PDF , Article$.
   Vascular Diseases Center, University of Ferrara, Ferrara, Italy
2. [embry10a] Embry AF: Integrating CCSVI and CNS autoimmunity in a disease model for MS. Int Angiol. 2010 Apr;29(2):93-4. PMID 20351664. PDF , Article$
   Direct-MS, Calgary, AL, Canada
3. [lee10a] Lee AB, Laredo J, and Neville R: Embryological background of truncular venous malformation in the extracranial venous pathways as the cause of chronic cerebro spinal venous insufficiency. Int Angiol. 2010 Apr;29(2):95-108. PMID 20351665. PDF , Article$.
   Department of Vascular Surgery, Georgetown University Hospital, Washington DC, USA.
4. [simka10b] Simka M, Kostecki J, Zaniewski M, Majewski E, and Hartel M: Extracranial Doppler sonographic criteria of chronic cerebrospinal venous insufficiency in the patients with multiple sclerosis. Int Angiol. 2010 Apr;29(2):109-14. PMID 20351666. PDF , Article$
   Department of Angiology, Private Healthcare Institution SANA, Pszczyna, Poland
5. [al-omari10a] Al-Omari MH, and Rousan LA: Internal jugular vein morphology and hemodynamics in patients with multiple sclerosis. Int Angiol. 2010 Apr;29(2):115-20. PMID 20351667. PDF , Article$.
   Radiology Department, King Abdullah University Hospital, Jordan University of Science and Technology, Jordan.
6. [menegatti10a] Menegatti E, Genova V, Tessari M, Malagoni AM, Bartolomei I, Zuolo M, Galeotti R, Salvi F, and Zamboni P: The reproducibility of colour Doppler in chronic cerebrospinal venous insufficiency associated with multiple sclerosis. Int Angiol. 2010 Apr;29(2):121-6. PMID 20351668. PDF , Article$.
   Vascular Diseases Centre, University of Ferrara, Italy
7. [hojnacki10a] Hojnacki D, Zamboni P, Lopez-Soriano A, Galleotti R, Menegatti E, Weinstock-Guttman B, Schirda C, Magnano C, Malagoni AM, Kennedy C, Bartolomei I, Salvi F, and Zivadinov R: Use of neck magnetic resonance venography, Doppler sonography and selective venography for diagnosis of chronic cerebrospinal venous insufficiency: a pilot study in multiple sclerosis patients and healthy controls. Int Angiol. 2010 Apr;29(2):127-39. PMID 20351669. PDF , Article$.
   The Jacobs Neurological Institute, State University of New York, Buffalo, NY, USA
8. [zamboni10b] Zamboni P, Menegatti E, Weinstock-Guttman B, Schirda C, Cox JL, Malagoni AM, Hojnacki D, Kennedy C, Carl E, Dwyer MG, Bergsland N, Galeotti R, Hussein S, Bartolomei I, Salvi F, Ramanathan M, and Zivadinov R: CSF dynamics and brain volume in multiple sclerosis are associated with extracranial venous flow anomalies: a pilot study. Int Angiol. 2010 Apr;29(2):140-8. PMID 20351670. PDF , Article$.
   Vascular Diseases Center, University of Ferrara-Bellaria Neurosciences, Ferrara and Bologna, Italy
9. [haacke10a] Haacke EM, Garbern J, Miao Y, Habib C, and Liu M: Iron stores and cerebral veins in MS studied by susceptibility weighted imaging. Int Angiol. 2010 Apr;29(2):149-57. PMID 20351671. PDF , Article$.
   Department of Radiology, Wayne State University, Detroit, MI, USA; Department of Radiology, the First Affiliated Hospital, Dalian Medical University, Dalian, China
10. [zivadinov10a] Zivadinov R, Schirda C, Dwyer MG, Haacke ME, Weinstock-Guttman B, Menegatti E, Heininen-Brown M, Magnano C, Malagoni AM, Wack DS, Hojnacki D, Kennedy C, Carl E, Bergsland N, Hussein S, Poloni G, Bartolomei I, Salvi F, and Zamboni P: Chronic cerebrospinal venous insufficiency and iron deposition on susceptibility-weighted imaging in patients with multiple sclerosis: a pilot case-control study. Int Angiol. 2010 Apr;29(2):158-75. PMID 20351672. PDF , Article$.
    Buffalo Neuroimaging Analysis Center, University at Buffalo, Buffalo, NY, USA
11. [malagoni10a] Malagoni AM, Galeotti R, Menegatti E, Manfredini F, Basaglia N, Salvi F, and Zamboni P: Is chronic fatigue the symptom of venous insufficiency associated with multiple sclerosis? A longitudinal pilot study. Int Angiol. 2010 Apr;29(2):176-82. PMID 20351673. PDF , Article$.
    Vascular Diseases Center, University of Ferrara, Ferrara, Italy
12. [bartolomei10a] Bartolomei I, Salvi F, Galeotti R, Salviato E, Alcanterini M, Menegatti E, Mascalchi M, and Zamboni P: Hemodynamic patterns of chronic cerebrospinal venous insufficiency in multiple sclerosis. Correlation with symptoms at onset and clinical course. Int Angiol. 2010 Apr;29(2):183-8. PMID 20351674. PDF , Article$.
    Center for Rare and Neuroimmunitary Diseases, Department of Neurological Science, Bellaria Hospital, Bologna, Italy
13. [plasmati10a] Plasmati R, Pastorelli F, Fini N, Salvi F, Galeotti R, and Zamboni P: Chronic cerebro-spinal venous insufficiency: report of transcranial magnetic stimulation follow-up study in a patient with multiple sclerosis. Int Angiol. 2010 Apr;29(2):189-92. PMID 20351675. PDF , Article$.
    Department of Neurology, Bellaria Hospital, Bologna, Italy2 Vascular Diseases Centre, University of Ferrara, Italy
14. [marrie10a] Marrie RA, Rudick R, Horwitz R, Cutter G, Tyry T, Campagnolo D, and Vollmer T: Vascular comorbidity is associated with more rapid disability progression in multiple sclerosis. Neurology. 2010 Mar;74(13):1041-7. PMID 20350978, doi:10.1212/WNL.0b013e3181d6b125, PDF , Article$. Interview.
    Health Sciences Center, GF-533, 820 Sherbrook Street, Winnipeg, MB R3A 1R9, Canada

Eine neue wissenschaftliche Publikationen ist erschienen:

• Simka M et al.: Reinterpreting the magnetic resonance signs of hemodynamic impairment in the brains of multiple sclerosis patients from the perspective of a recent discovery of outflow block in the extracranial veins. [simka10a]

Publikationen in Arbeit:

• Zamboni et al.: Endovascular Treatment for Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis: A Longitudinal, Magnetic Resonance Imaging, Blinded Pilot Study. [zamboni10a]
• Lee BB et al.: Embryological Background of Truncular Venous Malformation in the Extracranial Venous Pathways as the Cause of Chronic Cerebro-Spinal Venous Insufficiency. [prep_lee10a]

Prof. Dake hält am 14.03 einen Vortrag in Frontiers of IR bei der jährlichen Konferenz der interventionellen Radiologen über Stents für MS. Die Vorträge können über einen Webcast geschaut werden.

• Presentation: [pres_dake10b]
• Conference: [conf_sir10a]
• Webcast. Starts at 45' 30'', slide 356 and ends 1h04', slide 436.

Die Pilotstudie der Professoren Zamboni, Zivadinov und Weinstock-Guttman ist verfügbar.

Zamboni P, Menegatti E, Weinstock-Guttman B, Schirda C, Cox JL, Malagoni AM, Hojanacki D, Kennedy C, Carl E, Dwyer MG, Bergsland N, Galeotti R, Hussein S, Bartolomei I, Salvi F, and Zivadinov R:
The severity of chronic cerebrospinal venous insufficiency in patients with multiple sclerosis is related to altered cerebrospinal fluid dynamics. [zamboni09h]

An der UIP Konsensuskonferenz^[uip09] über venöse Missbildungen – geführt von Prof. Byung B Lee – und Experten aus 47 Ländern – wurden die Fakten studiert und einstimmig für die Aufnahme der in CCSVI gefundenen stenosierenden Läsionen in das neue Konsensus- und Leitlinien-Dokument gestimmt.

[lee09a]

Dieses Dokument kann interventionellen Radiologen und Gefässchirurgen gegeben werden. CCSVI Läsionen sind als nun als venöse Missbildungen, welche angeboren und MS Läsionen vorausgehen, klassifiziert.

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